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Should You Take CoQ10 If You're on a Statin?
CoQ10 and statins is a question for your prescriber. NCCIH says CoQ10 does not appear to relieve statin muscle pain, so it is not a proven fix. The popular idea that statins lower the body's CoQ10 is a theory in the sources we hold. Synaptril contains CoQ10 as ubiquinone.
Written by the Synaptril label deskUpdated · 4 min read
Does CoQ10 help if you take a statin?
CoQ10 does not appear to relieve statin muscle pain, according to NCCIH (NCCIH, Coenzyme Q10).
The theory behind the question is that statins may lower the body's own CoQ10. We hold no source that measures it, so we treat it as an idea. NCCIH also calls the evidence for CoQ10 in heart disease inconclusive (NCCIH, Coenzyme Q10).
Is the CoQ10 in Synaptril a statin fix?
No. Synaptril lists CoQ10 last in its blend, at no more than about 35 mg a capsule, and sells no statin claim. Trials used about 30 to 300 mg a day for heart failure, so the capsule sits at the low end of that range at most (Linus Pauling Institute, Coenzyme Q10).
| Question | Answer from our sources |
|---|---|
| Relieves statin muscle pain? | Does not appear to (NCCIH, Coenzyme Q10) |
| Safe with every medicine? | May weaken warfarin (Linus Pauling Institute, Coenzyme Q10) |
How do you check CoQ10 against your medicines?
Choose your medicine type, then read which ingredient matters.
Blood thinners (warfarin)
- Coenzyme Q10Reported to reduce warfarin's effect; your INR may need checking. (Linus Pauling Institute, Coenzyme Q10)
Diabetes medicines
- Alpha lipoic acidMay lower blood sugar further; check your glucose more often. (Linus Pauling Institute, Lipoic Acid)
Antibiotics (tetracyclines, quinolones)
- MagnesiumBinds these antibiotics; take them at least 2 hours before or 4-6 hours after. (NIH ODS, Magnesium)
Osteoporosis drugs (bisphosphonates)
- MagnesiumCan reduce absorption; separate by at least 2 hours. (NIH ODS, Magnesium)
Water pills and acid reducers (PPIs)
- MagnesiumThese drugs change magnesium levels; your doctor may check them. (NIH ODS, Magnesium)
Seizure medicines
- L-carnitineValproic acid and some other seizure drugs lower carnitine levels; ask your neurologist. (NIH ODS, Carnitine)
Liver problems or many medicines
- TurmericRare liver injury, mostly with high-absorption curcumin; stop and call a doctor for dark urine or yellow skin. (NIH LiverTox, Turmeric)
A starting list for a talk with your pharmacist, not a full interaction check. Keep taking prescribed medicine; never stop or change a dose because of a supplement.
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See packsWho decides whether to add CoQ10 to a statin?
Your prescriber and pharmacist decide, because they know your medicines.
- Bring the Synaptril bottle to your pharmacist
- Report new muscle pain to your prescriber
- Ask about warfarin if you take it too
Never stop a statin because of muscle pain or a supplement. See supplements and medicines and CoQ10 side effects.
FAQ01
Synaptril questions people ask
Do statins lower CoQ10?
That is a common theory, but the sources we hold do not measure it, so we will not state it as fact.
Can CoQ10 stop statin muscle pain?
Not according to NCCIH, which says CoQ10 does not appear to relieve it. Report muscle pain to your prescriber instead of treating it yourself.
Does the CoQ10 in Synaptril matter for statin users?
We hold no statin interaction for CoQ10, but the label asks you to consult a physician first.
What should I tell my prescriber about CoQ10?
Say that you take it, the product name and the daily dose, which Synaptril does not print. CoQ10 may change how warfarin works, so say so if you take that too.
Who wrote this02
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Pages built from the label, the sales page and linked NIH, FDA, CDC, FTC and peer-reviewed sources.
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