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What's Inside Synaptril's 575 mg Proprietary Blend?
The Synaptril proprietary blend is 575 mg per capsule, shared by magnesium glycinate, alpha lipoic acid, butcher's broom, L-carnitine, turmeric extract and coenzyme Q10. The label prints the total, not the single amounts. Simple arithmetic shows that magnesium glycinate takes most of it, so the other five are small.
Written by the Synaptril label deskUpdated · 4 min read

What is the Synaptril proprietary blend?
The Synaptril proprietary blend is a group of six ingredients listed under one total weight, 575 mg. US rules let a blend show only that total, then list the ingredients from most to least by weight (21 CFR 101.36, Supplement Facts).
So the order tells you rank, not amounts: magnesium glycinate first, coenzyme Q10 last. Magnesium is the exception, because nutrients with a Daily Value must show their amount: 80 mg.
How much of the 575 mg is magnesium glycinate?
Most of it. Magnesium glycinate is about 14% magnesium by weight (GlobalRPH, Magnesium Glycinate), so 80 mg of magnesium needs about 567 mg of the compound.
575 minus 567 leaves about 8 mg for the other five. Even with a richer 20% grade, it takes 400 mg, leaving at most 175 mg for all five together.
Can typical studied doses fit inside the blend?
No, not together. Studied doses of alpha lipoic acid (200-1,800 mg a day) and CoQ10 (30-300 mg for heart trials) cannot all fit in what is left (Linus Pauling Institute, Lipoic Acid) (Linus Pauling Institute, Coenzyme Q10).
The ceilings below come from label order plus the magnesium math. They are upper limits, not measurements; the real amounts are not printed.
| Blend line | Most per capsule |
|---|---|
| Alpha lipoic acid | 175 mg |
| Butcher's broom | 88 mg |
| L-carnitine | 58 mg |
| Turmeric extract | 44 mg |
| Coenzyme Q10 | 35 mg |

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See packsWhat if the magnesium share is higher or lower?
A richer magnesium grade frees more room in the blend, and a leaner one frees less. The label does not say which grade is used.
Move the slider to test both ends. The room left for the other five changes fast, which is why the ceilings above are stated as "at most".
At 14.1%, 80 mg of magnesium needs about 567 mg of magnesium glycinate. That leaves about 8 mg for alpha lipoic acid, butcher's broom, L-carnitine, turmeric and CoQ10 together.
- Magnesium glycinate567 mg
- Alpha lipoic acidat most 8 mg
- Butcher's broomat most 4 mg
- L-carnitineat most 3 mg
- Turmeric (95% curcuminoids)at most 2 mg
- Coenzyme Q10at most 2 mg
Arithmetic from the label (80 mg magnesium, 575 mg blend, listed most to least by weight (21 CFR 101.36, Supplement Facts)) and the magnesium share of magnesium glycinate (GlobalRPH, Magnesium Glycinate). The exact grade used is not printed, so we show the range. Ceilings, not amounts.
What can you not tell from a proprietary blend label?
You cannot tell the exact amount of five of the six ingredients. No lab report is published, so the ceilings are all we have.
Blends are legal, and they do not prove a low dose. A maker who shared the single amounts would settle the question; asking the order desk is a fair step.
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See the Synaptril supplement facts, all ingredients and a comparison with other brain supplements. Related: what a proprietary blend is.
FAQ01
Synaptril questions people ask
Why does Synaptril not list each ingredient amount?
US rules let a proprietary blend show only its total weight. Synaptril shows 575 mg for the blend and a separate amount for magnesium, but no single amounts for the other five.
Is a proprietary blend a sign of a low dose?
Not by itself. Here, though, the magnesium arithmetic leaves little room, so the five hidden amounts are small whatever the reason for the format.
Which Synaptril ingredient is the largest in the blend?
Magnesium glycinate, because the label lists it first and 80 mg of magnesium needs roughly 400-567 mg of the compound.
Who wrote this02
Written and reviewed by
Pages built from the label, the sales page and linked NIH, FDA, CDC, FTC and peer-reviewed sources.
Last updated . Learn about our editorial standards and how we check reviews. This website is run by a U.S. retail partner of Synaptril, not by the manufacturer or the distributor. We make money when you buy through our order links.
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